hrp0094p2-305 | Growth and syndromes (to include Turner syndrome) | ESPE2021

Anastrozole improves height prediction and near final height as monotherapy or in combination with growth hormone

Machado Pinto Renata , de Almeida Debora Ribeiro , Vitor Percussor Silva Joao ,

Introduction: The wide aromatization of androgens during puberty is responsible for the rapid bone maturation at this age. In this context, the use of aromatase inhibitors (AIs) has been justified by the potential to slow down the advancement of bone age and thus improve growth. For more than two decades, studies have pointed out the validity of AIs to improve the predicted final height (PFH). However, data on near-final height (NFH) of children treated with A...